We are currently based at the Stevenage Bioscience Catalyst and our team is expanding.  We provide extraordinary career opportunities for talented individuals, who will have the opportunity to work with highly experienced leaders in science and business with proven track records in building successful businesses.  Our success depends on the quality, experience and ambition of the individuals that join our team.

This is an opportunity to help build Gyroscope into a world class gene therapy company, so if you would like to become a part of our dynamic team and contribute towards preventing the devastating impact of sight loss, please contact:

Gyroscope is an equal opportunity employer committed to a culturally diverse and international team.

Please note that Gyroscope does not accept speculative applications from recruitment agencies.

Open Positions

To take the next exciting step in your career, please review our list of current openings and job descriptions below. To apply, please submit your CV and a cover letter to

Gyroscope does not accept speculative applications from recruitment agencies.


This position will report into the VP, Translational Research

The (Senior) Co-ordinator, Nonclinical Operations will act as study monitor and co-ordinate activities across project boundaries with other functional areas within Translational Research. The (Senior) Co-ordinator will oversee work placed at Contract Research Organisations (CROs), anticipate obstacles related to timelines and resource allocation, and will troubleshoot and resolve these obstacles. The expectation is that this individual will also serve as Study Monitor for assigned studies and represent translational research on project teams. The successful candidate will have the ability to complete work in a resourceful, self-sufficient manner and is able to design alternative approaches to achieve desired outcomes.

Key Responsibilities:

  • Responsible for operational oversight, and on-site monitoring of nonclinical studies conducted at CROs
  • Serves as Study Monitor on non-GLP and GLP-compliant studies conducted at CROs, working closely with more senior programme representatives/project toxicologists
  • Participates in the selection of CROs via technical assessments
  • Communicates timing, budget and monitor the study conduct, as appropriate
  • Collaborates with project team to develop study designs
  • Provide oversight from protocol development through reporting, including reviewing/editing reports and status updates from CROs, problem solving issues and providing recommendations for appropriate course of action
  • Applies thorough knowledge of GLP/regulatory requirements to all aspects of study preparation and oversight
  • May assist in the preparation of internal documents and Regulatory submissions, including authoring (under supervision)
  • Performs other duties as assigned

Required attributes:

  • Proven ability to simultaneously manage multiple highly complex short and long-term projects
  • Knowledgeable of study design considerations for all types of non-clinical studies
  • Extensive knowledge of nonclinical safety and pharmacology operations, including past study monitoring experience
  • Knowledge of national and international regulatory requirements relating to nonclinical safety studies
  • Possesses a distinguished record enabling the goals of the assigned projects
  • Demonstrates excellence in his/her own discipline and/or area of pursuit. Demonstrated strong aptitude to lead a group or team endeavour and building team unity. Demonstrated
    ability to compile and analyse study data with limited oversight
  • Excellent verbal presentation and written skills
  • Demonstrated ability to solve complex problems to attain crucial project goals


  • Ph.D. (or equivalent degree) and 4-7 years relevant work experience, or
  • M.S. (or equivalent degree) and 7+ years relevant work experience, or
  • B.S. (or equivalent degree) and 10+ years of relevant work experience
  • Project Management qualification an advantage but not essential

If interested in applying for the above position please submit your CV and a covering letting to

Closing date for applications is Friday 21st December 2018

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Open position for Research Assistant in gene therapy company

The successful candidate will join Gyroscope’s highly active research team which is responsible for the delivery of novel adeno-associated virus (AAV) construct designs and early in vitro and in vivo proof-of-concept studies (PoC) for candidates in pre-clinical development. He or she will support all aspects of the projects from early phases and the subsequent transition to clinical development, as well as supporting subsequent vector manufacture and testing. The role will involve supporting the initiation and subsequent development of innovative improvements in the design, characterisation and manufacture of gene therapy medicines.

The position will be based in Stevenage, Hertfordshire, UK.

Required skills
• Experience in histological techniques, including sectioning, mounting, staining and visualising samples;
• Experience in molecular techniques (such as cloning, PCR, agarose gel electrophoresis);
• Preparation and maintenance of accurate laboratory records.

Desirable skills
• Experience in cell and tissue culture, working under aseptic conditions;
• Experience in assay development (particularly sandwich ELISA, cell-based assays, functional ELISA-based assays);
• Experience in gene therapy development or methods for the design and generation of biopharmaceutical viral vectors;
• Background in ophthalmology, immunology and/or complement research;
• Experience in industry.

Activities and responsibilities
• Conducting research experiments to support early candidate evaluation and subsequent selection;
• Development of new viral vectors to answer research questions or improve current techniques;
• Ensuring all required documentation and experimental records are completed and approved in a timely manner, ensuring validity and reliability of data at all times;
• Effective cross-functional interaction with other departments in Gyroscope;
• Ability to prioritise and deliver projects on time.

We understand that the perfect candidate does not necessarily combine all required/desirable skills and encourage all interested candidates that fulfil at least some of the requirements to apply.

The application should include a one-page cover letter outlining how you meet the required competencies for this role at Gyroscope Therapeutics as outlined in the job requirements above. This letter should be accompanied by a current curriculum vitae. Interested applicants should submit their applications to

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